This patient is more likely to have suboptimal Vitamin D levels. The issue of suboptimality depends on which genes have suboptimal variations. Poor CYP2R1 function means reduced conversion of Vitamin D from D2 to D3 (activated form).

Poor GC/VDBP function means reduced transport of Vitamin D from site of activation to site of function. Poor VDR function means reduced ability of Vitamin D to bind to its receptor and activate its functions in the body.

Serum D levels should be assessed before instituting therapy and afterwards to assess/monitor progress.
When vitamin D therapy is indicated, always use Vitamin D3.
Vitamin D supplementation should be offered during the day, ideally in the morning.
For those with suboptimal GC, daily divided dosing is recommended.
Magnesium should be offered concurrently to support vitamin D absorption and utilization.

Get direct skin exposure to natural sunlight, especially first thing in the morning.
Vitamin D3 supplementation should be taken during the morning hours.

This patient is more likely to have a poor anti-inflammatory response. In the case of viral or bacterial infections, this patient may be more likely to exhibit more severe symptoms.
They may be more likely to exhibit "cytokine storms" or another form of a severe immune reaction.
They are at an increased risk of a poor autoimmune response and are more likely to struggle with things like brain fog, migraines, fatigue, and other forms of myalgia.

Vitamin B12 (methylated form if MTR genotype is AA, adenosyl form if otherwise).
Vitamin B12 dosage based on further objective test results of levels in urine or serum.
Vitamin B9 (methylated form if SHMT1 genotype is GG, non-methylated forms such as folinic acid or folic acid if otherwise).
Vitamin B6
SAMe (except if the patient also carries AA genotype for COMT)

Prioritize vitamin B rich foods (mainly B12, B6, B2, and B9) found in sustainable fish, organic eggs, organic spinach, beer yeast, and nutritional yeast
Additional anti-inflammatory and methylation support should be offered to suboptimal methylators who are on a plant-based diet.

This patient is more likely to have suboptimal glutathionization function. Their ability to effectively render toxins harmless and remove them from the body is considered suboptimal.
0 copies of GSTT1 or GSTM1: They are more likely to struggle with fatigue, lack of energy and tiredness, particularly when exposed to chemicals or after periods of sustained exercise or physical activity.
GG or AG GSTP1: They are more likely to struggle with strong smells, chemicals, parfums, and other odorizers. They may complain of frequent migraines and headaches, particularly when exposed to chemicals or other environmental toxins such as cigarette smoke, mould, or pollution.

Youtrients Detox Optimizer
NAC
Milk Thistle
Selenium
Manganese
Alpha Lipoic Acid
Vitamin C
Magnesium
Sulforaphane

Avoid spending excessive time in toxic environments such as designated smoking areas, high pollution environments, moldy environments, and areas with high pesticide use
Focus on getting enough deep, rested sleep at night
Eat bitter vegetables for increasing liver support.

This patient carries the normal or optimal profile

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